Boreal’s linked molecule patent portfolio includes alternate chemistries for high-accuracy sequencing, targeted ligation of unknown gene fusions and other applications.
- Duplex sequencing without the use of molecular barcodes or tags for ultra-low error detection (Pro-Seq)
- Targeted ligation to desired sequences of interest for applications such as:
- Detection of gene fusions with unknown partners
- Singe-stranded DNA & RNA library prep and target capture
- Amplification-free target capture for single molecule sequencing